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2 edition of Angiogenesis in endocrine tissues found in the catalog.

Angiogenesis in endocrine tissues

Angiogenesis in endocrine tissues

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Published by Research Signpost in Trivandrum .
Written in English


Edition Notes

Includes bibliographical references.

Statementeditor, Isabelle Vilgrain ; co-editor, Jean-Jacques Feige.
ContributionsVilgrain, Isabelle., Research Signpost (Trivandrum, India)
The Physical Object
Pagination230 p. :
Number of Pages230
ID Numbers
Open LibraryOL23679919M
ISBN 10813080090X
LC Control Number2009346472


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Angiogenesis in endocrine tissues Download PDF EPUB FB2

Angiogenesis has recently played a critical role in regulation of adipose tissue expansion and regression. Like most other tissues in the body, adipose expansion and regression is accompanied by alteration of blood vessel density and structures.

The vascular alteration plays an active role in regulation of adipose tissue size and : $ Angiogenesis has recently played a critical role in regulation of adipose tissue expansion and regression.

Like most other tissues in the body, adipose expansion and regression is accompanied by alteration of blood vessel density and structures. The vascular alteration plays an active role in. Angiogenesis is the growth of blood vessels from the existing vasculature.

It occurs throughout life in both health and disease, beginning in utero and continuing on through old age. No metabolically active tissue in the body is more than a few hundred micrometers from a blood capillary, which is formed by the process of by: 4.

Abstract. Angiogenesis promotes the growth of tumors, because it both facilitates oxygenation and nutrient flow, and removes metabolic waste. During the past two decades, as the importance of tumor vascularity became recognized, angiogenesis and the relationship between blood vessels and tumor progression received increasing by: Angiogenesis has recently played a critical role in regulation of adipose tissue expansion and regression.

Like most other tissues in the body, adipose expansion and regression is accompanied by alteration of blood vessel density and structures.

Angiogenesis in endocrine tissues book vascular alteration plays an active role in regulation of adipose tissue size and functions. Abstract. Angiogenesis is the growth of blood vessels from the existing vasculature.

The field of angiogenesis has grown enormously in the past 30 years, with only 40 papers published in and nearly in Why has there been this explosive growth in angiogenesis research.

Angiogenic therapies provide a potential to conquer cancer. Encyclopedia of Endocrine Diseases, Second Edition, comprehensively reviews the extensive spectrum of diseases and disorders that can occur within the endocrine system.

It serves as a useful and comprehensive source of information spanning the many and varied aspects of the endocrine end metabolic system. We speculate that ovarian steroids influence endothelial cell functions with respect to angiogenesis in a tissue-specific manner. Because the uterus is a major target for E and P 4, and because heterogeneous cell types of the uterus respond differently to these hormones in a dynamic manner, we suspect that uterine endothelial cells respond to Cited by:   The organization of the murine VEGF gene has been also described (59).

Similarly to the human gene, the coding region of the murine VEGF gene encompasses approximately 14 kb and is comprised of eight exons interrupted by seven introns. Analysis of exons suggests the generation of three isoforms, VEGFCited by: Angiogenesis This book covers the following topics: Origin of Blood Vessels, Angiogenesis Assays, Role Of Adenosine in Metabolic Regulation of Vascular Growth, Regulation: Metabolic Factors and Mechanical Factors.

The concept is emerging that tissue PRAS is one such locally active regulatory system. With more and more reproductive and endocrine organs being added to the list of tissues that contain a local tissue PRAS, questions are being raised by the reproductive biologists and endocrinologists as to the role of such systems in the tissues of their.

Angiogenesis in endocrine neoplasms Angiogenesis in endocrine neoplasms Jugenburg, Martin; Kovacs, Kalman; Jugenburg, Ivan; Scheithauer, Bernd Angiogenesis promotes the growth of tumors, because it both facilitates oxygenation and nutrient flow, and removes metabolic waste.

During the past two decades, as the importance of tumor vascularity became recognized, angiogenesis Missing: book. Here we report on the identification of an angiogenic mitogen selective for one endothelial cell type, endocrine gland endothelium.

Remarkably, the expression of this factor is largely restricted Cited by: Angiogenesis versus vasculogenesis. Lack of oxygen and nutrients threatens the tissue integrity and viability fundamentally. In these situations of undersupply, the organisms´ reaction is to improve the local perfusion by inducing the growth of the by: 7.

Tissues of all types are vulnerable to injury and, inevitably, aging. In the former case, understanding how tissues respond to damage can guide strategies to aid repair.

In the latter case, understanding the impact of aging can help in the search for ways to diminish its effects. Inflammation is the standard, initial response of the body to injury. As one of the largest endocrine organs in the body, adipose tissue secrets a number of bioactive hormones, called adipokines.

The expression and secretion of adipokines are tightly controlled and coordinated by physiological and pathophysiological conditions. In multiple physiological conditions, such as obesity, cold adaptation, exercise training, expression and secretion of adipokines are Author: Hannah Xiaoyan Hui, Tianshi Feng.

Exposure of humans and rodents to cold activates thermogenic activity in brown adipose tissue (BAT). This protocol describes a mouse model to study the activation of BAT and angiogenesis in adipose tissues by cold acclimation. The pancreas is a long, slender organ, most of which is located posterior to the bottom half of the stomach (Figure ).

Although it is primarily an exocrine gland, secreting a variety of digestive enzymes, the pancreas has an endocrine function. Its pancreatic islets —clusters of cells formerly known as the islets of Langerhans. The endocrine system coordinates with the nervous system to control the functions of the other organ systems.

Cells of the endocrine system produce molecular signals called hormones. These cells may compose endocrine glands, may be tissues or may be located in organs or tissues that have functions in addition to hormone production.

Angiogenesis, the formation of new blood vessels, is a complex process that involves the migration, growth, and differentiation of endothelial cells lining the inner walls of blood vessels.

Angiogenesis is a well-orchestrated process that is regulated by different. Angiogenesis is required for the growth and expansion of both healthy and pathological tissues.

The plasticity of the adipose tissue is reflected by its remarkable ability to expand or to reduce. Topics covered includes: Homeostasis, Cell Physiology, Integumentary System, The Nervous System, Senses, The Muscular System, Blood Physiology, The Cardiovascular System, The Immune System, The Urinary System, The Respiratory System, The Gastrointestinal System, Nutrition, The Endocrine System, The Male Reproductive System, The Female Reproductive System, Pregnancy and Birth, Genetics.

Angiogenic control has proven to be one of the most difficult aspects of tissue engineering to master. This presents broad-based anatomic and physiologic challenges to the tissue engineer.

Key controllers of angiogenesis have been formed to be mechanical forces, small molecules (drugs and growth factors), co-culture with non-vascular cells, biomaterials, and stem cells. Angiogenesis in health and disease Peter Carmeliet Blood vessels constitute the first organ in the embryo and form the largest network in our body but, sadly, are also often deadly.

When dysregulated, the formation of new blood vessels contributes to numerous malignant, ischemic, inflammatory, infectious and immune Size: KB. In epithelial tissue, cells are closely packed with little or no extracellular matrix except for the basal lamina that separates the epithelium from underlying tissue.

The main functions of epithelia are protection from the environment, coverage, secretion and excretion, absorption, and filtration.

Cells are bound together by tight junctions. Angiogenesis has recently played a critical role in regulation of adipose tissue expansion and regression.

Like most other tissues in the body, adipose expansion and regression is accompanied by alteration of blood vessel density and : Springer New York. Adipose tissue has been recognized as a complex organ with endocrine and metabolic roles. The excess of fat mass, as occurs during overweight and obesity states, alters the regulation of adipose tissue, contributing to the development of obesity-related disorders.

In this regard, many epidemiological studies shown an association between obesity and numerous types of malignancies, comprising Cited by: 4. In Vitro Angiogenesis Properties of Endothelial Progenitor Cells: A Promising Tool for Vascularization of Ex Vivo Engineered Tissues.

Günter Finkenzeller, Nestor Torio-Padron, Arash Momeni, Alexander T. Mehlhorn, and ; G. Björn Stark; Pages: –   The known endothelial mitogens stimulate growth of vascular endothelial cells without regard to their tissue of origin.

Here we report a growth factor that is expressed largely in one type of Cited by: ii. secrete bioactive molecues (prostacyclin, thrombomodulin, heparin, tissue factor, plasminogen activator) iii. mediate angiogenesis and normal microvascular growth iv. transport molecules from blood to interstitium v.

interact with adjacent mural cells (i.e. smooth muscle) during growth and disease. Angiogenesis has recently played a critical role in regulation of adipose tissue expansion and regression. Like most other tissues in the body, adipose expansion and regression is accompanied by alteration of blood vessel density and structures.

The vascular alteration plays an active role in regulation of adipose tissue size and : Springer New York. In this chapter, we examine the contributions of endocrine hormones-small molecules (steroids) and peptides-to regulation of angiogenesis.

Most of the hormones considered appear to have actions on blood vessels only in specific tissues, but the angiogenic properties of these substances have not been systematically studied in tissues other than Author: Paul J.

Davis, Paul J. Davis, Shaker A. Mousa, Faith B. Davis, Hung Yun Lin. Keywords:neuropeptide, angiogenesis, chromogranin, secretogranin, neurogenic inflammation, neuroendocrine. Abstract: Secretoneurin (SN) represents a 33 amino acid neuropeptide, which is highly conserved between mammals, reptiles, birds, amphibians and fish.

It is specifically expressed in endocrine, neuroendocrine and neuronal tissues. Angiogenesis inhibitors are unique cancer-fighting agents because they block the growth of blood vessels that support tumor growth rather than blocking the growth of tumor cells themselves.

Angiogenesis inhibitors interfere in several ways with various steps in blood vessel growth. Angiogenesis Inhibitors: Block tumor growth by preventing angiogenesis (growth of blood vessels) With age, muscles and other tissues waste from a loss of cells, a process termed ___________ Atrophy.

Gene expression array analysis performed in our group identified a considerable number of genes deregulated in rat pituitary tumors compared to normal pituitary tissues.

Some of the deregulated transcripts are associated with angiogenesis, including vascular endothelial growth factor (Vegf), angiopoietin-1 (Ang-1) and -2 (Ang-2).Author: Ninelia Minaskan Karabid, Michael Atkinson, Natalia Pellegata. Historically adipose tissue has been widely studied and accepted in its function as an energy shop and metamorphosis.

It is merely in the last 15 old ages that it has a recognized function in reacting to nervous, alimentary and hormonal signals and releasing adipokines that control feeding, thermogenisis, unsusceptibility and neuroendocrine mone variety meats have traditionally.

Endothelial-pericyte interactions in angiogenesis. Cell Tissue Res 15–23, Crossref PubMed ISI Google Scholar; Gidlund Ek Ydfors M, Appel S, Rundqvist H, Sundberg CJ, Norrbom JM.

Rapidly elevated levels of PGC-1α-b protein in human skeletal muscle after exercise: exploring regulatory factors in a randomized controlled by: Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels, formed in the earlier stage of enesis continues the growth of the vasculature by processes of sprouting and splitting.

Vasculogenesis is the embryonic formation of endothelial cells from mesoderm cell precursors, and from neovascularization, although discussions MeSH: D   The proposed pathogenic roles of MMPs in cancer are tissue breakdown and remodeling during invasive tumor growth and tumor angiogenesis.

Tissue inhibitors of metalloproteinases (TIMPs) form a complex with MMPs, which in turn inhibits active by:. Angiogenesis, formation of new blood vessels.

Angiogenesis is a normal process during growth of the body and in the body’s replacement of damaged tissue. However, it can also occur under abnormal conditions, such as in tumour progression. At some point, after months or even years as a harmlessMissing: book.Surprisingly, in the bovine tissues, the pattern of EG-VEGF/PROK1 and Bv8/PROK2 expression appears closer to the distribution in the mouse than in the human tissues: EG-VEGF/PROK1 is more abundantly expressed in liver than in endocrine by:   Secreted Protein, Acidic and Rich in Cysteine (SPARC), a kDa matricellular glycoprotein, is also known as osteonectin and BM It was initially found to be secreted from bone (), but SPARC is expressed in most tissues and was the first extracellular matrix protein described in adipose tissue (2,3).SPARC is a multifunctional protein: it is involved in osteogenesis, angiogenesis, Cited by: